Journal: ACS Omega
Article Title: Characterization of the Interaction between Human α 1 ‑Acid Glycoprotein and Apremilast Enantiomers: HPLC, Isothermal Titration Calorimetry, Ultracentrifugation, and Docking Studies
doi: 10.1021/acsomega.5c07756
Figure Lengend Snippet: Some representative chromatograms from the HPLC study on a chiral AGP column at 25 °C. R and S denote the enantiomers of APR. (A) Eluent is 95% sodium phosphate buffer 5% IPA. (B) Eluent is 95% ammonium acetate buffer 5% IPA. (C) Eluent is 95% ammonium bicarbonate 5% IPA. Flow rate: 0.7 mL/min. The detection wavelength was set at 230 nm.
Article Snippet: The chiral AGP column (ChromTech Chiral-AGP) with dimensions of 150 mm × 4.0 mm was sourced from ChromTech Ltd. (Congleton, UK).
Techniques: